Artificial Intelligence-Based Cyber Threat Detection and Response for Critical Infrastructure Security

Main Article Content

Reily Kaium
Lizi Alasa
Kurtz Robert
Okuma Kaium
Kurtz Diana

Abstract

The rapid digital transformation of critical infrastructure has significantly increased its exposure to complex and continuously evolving cyber threats, creating an urgent need for intelligent and adaptive cybersecurity solutions. Conventional security mechanisms, such as signature-based and rule-based intrusion detection systems, often struggle to identify novel attack patterns and provide timely responses to emerging threats. To address these limitations, this study proposes an artificial intelligence (AI)-driven framework for cyber threat detection and automated response that strengthens the security, resilience, and operational reliability of critical infrastructure environments. The experimental evaluation demonstrates that AI-based techniques substantially outperform traditional cybersecurity methods in terms of detection performance. Conventional rule-based systems achieve an average detection accuracy of approximately 68%, whereas machine learning and deep learning models improve the accuracy to nearly 80% and 88%, respectively. The proposed AI-driven framework delivers the highest performance, achieving an overall detection accuracy of approximately 94%. This superior performance highlights its capability to accurately identify both previously known attacks and sophisticated zero-day threats. Beyond detection accuracy, the study evaluates response time, which plays a crucial role in limiting the impact of cyber incidents. The findings reveal that the proposed AI-enabled response mechanism reduces the average response time to approximately 35 seconds, compared with around 150 seconds for manual response processes and 90 seconds for conventional rule-based automation. Such improvements enable faster threat containment, minimize operational disruption, and enhance the resilience of critical infrastructure systems. The framework also demonstrates notable improvements in reducing false positive alerts. The AI-driven approach achieves a false positive rate of approximately 5%, significantly lower than the 20% observed in signature-based systems and the 12% reported for anomaly-based detection methods. By minimizing false alarms, the proposed framework improves the efficiency of security operations, reduces alert fatigue among cybersecurity analysts, and enables security teams to prioritize genuine threats more effectively.

Article Details

How to Cite
Kaium, R., Alasa, L., Robert, K., Kaium, O., & Diana, K. (2026). Artificial Intelligence-Based Cyber Threat Detection and Response for Critical Infrastructure Security. The Eastasouth Journal of Information System and Computer Science, 4(01), 1–16. https://doi.org/10.58812/esiscs.v4i01.1166
Section
Articles

References

[1] M. A. Sami, M. L. Rahman, Z. A. Tanni, Z. S. Munmun, S. Nusrat, and B. Biswas, “Artificial intelligence and big data for precision medicine: A review of bioinformatics-driven healthcare applications,” Frontiers in Computer Science and Artificial Intelligence, vol. 5, no. 6, pp. 36–43, 2026. doi: 10.32996/fcsai.2026.5.6.7.

[2] S. N. Hasan, A. S.-A. Alahi, A. Al Zaiem, H. Kaur, M. T. B. Ansar, and J. Kaur, “Self-healing cybersecurity systems using RL agents,” in Proc. 2025 1st International Conference on Advancement in Futuristic Technologies (ICAFT), pp. 1–8, 2025, doi: 10.1109/ICAFT66710.2025.11452866.

[3] S. M. Orthi, T. R. Sikder, S. M. M. Uddin, T. Roy, M. J. Hossain, and M. I. Faruk, “DataOps-oriented big data governance for automated decision pipelines,” in Proc. 2025 1st International Conference on Advancement in Futuristic Technologies (ICAFT), Belagavi, India, pp. 1–8, 2025, doi: 10.1109/ICAFT66710.2025.11452860.

[4] M. I. Hasan, C. Barua, M. S. Rahman, K. R. Alam, J. U. Z. Kabir, and K. R. H. Saurav, “Resilient healthcare and critical urban infrastructure design using AI-driven engineering and project management systems,” Journal of Medical and Health Studies, vol. 4, no. 6, pp. 20–34, 2023. doi: 10.32996/jmhs.2023.4.6.20.

[5] C. Barua, M. S. Rahman, M. I. Hasan, K. R. H. Saurav, K. R. Alam, and J. U. Z. Kabir, “AI-Driven Digital Twin Frameworks for Predictive Maintenance and Process Optimization in Smart Battery Manufacturing for Electric Vehicles,” Academica Global: Journal of Computer Science and Technology Studies, vol. 3, no. 1, pp. 39-51, 2024. doi: 10.32996/agjcsts.2024.3.1.4.

[6] K. R. Alam, K. R. H. Saurav, J. U. Z. Kabir, M. S. Rahman, M. I. Hasan, and C. Barua, “AI-driven digital marketing analytics and leadership strategies for sustainable business innovation: A mixed-methods research study,” The American Journal of Management and Economics Innovations, vol. 6, no. 12, pp. 83–102, 2024. [Online]. Available: https://theamericanjournals.com/index.php/tajmei/article/view/7400.

[7] J. Kaur et al., “Comparative analysis of transformer and LSTM architectures for cybersecurity,” EAI Transactions, 2025.

[8] N. Das, H. Kaur, K. B. Siddiqa, S. N. Hasan, P. Chakraborty, J. Kaur, H. Rahman, A. S.-A. Alahi, and R. Hasan, “AI-driven threat detection and response framework for protecting U.S. critical infrastructure from cyberattacks,” International Cybersecurity Law Review, 2026, doi: 10.1365/s43439-026-00169-5.

[9] S. Islam, S. I. Khan, A. A. M. Ashik, E. Hossain, M. M. Rahman, and M. S. Rahman, “Big data in economic recovery: A policy-oriented study on data analytics for crisis management and growth planning,” Journal of Computational Analysis and Applications (JoCAAA), vol. 33, no. 7, pp. 2349–2367, 2024. [Online]. Available: https://www.eudoxuspress.com/index.php/pub/article/view/3338.

[10] M. Kamruzzaman, R. S. Mondal, M. K. Islam, M. A. Rahaman, and S. Saha, “AI-driven predictive modelling of US economic growth using big data and explainable machine learning,” International Journal of Computational and Experimental Science and Engineering, vol. 10, no. 4, pp. 1927-1938, 2024. doi: 10.22399/ijcesen.3612.

[11] S. I. Khan, M. S. Rahman, A. A. M. Ashik, S. Islam, M. M. Rahman, and E. Hossain, “Big data and business intelligence for supply chain sustainability: Risk mitigation and green optimization in the digital era,” European Journal of Management, Economics and Business, vol. 1, no. 3, pp. 262–276, 2024, doi: 10.59324/ejmeb.2024.1(3).23.

[12] M. S. Rahman, S. Islam, S. I. Khan, A. A. M. Ashik, E. Hossain, and M. M. Rahman, “Redefining marketing and management strategies in digital age: Adapting to consumer behavior and technological disruption,” Journal of Information Systems Engineering and Management, vol. 9, no. 4, pp. 1–16, 2024. [Online]. Available: https://www.jisem-journal.com/download/32_AM-Manuscript-Digital_Marketplace-JISEM.pdf.

[13] J. U. Z. Kabir, K. R. H. Saurav, M. S. Rahman, M. I. Hasan, C. Barua, K. R. Alam, and M. M. Rahman, “Financially sustainable strategic leadership and management with predictive analytics to strengthen nationwide U.S. healthcare quality and performance,” European Journal of Medical and Health Research, vol. 1, no. 3, pp. 144–150, 2023, doi: 10.59324/ejmhr.2023.1(3).24.

[14] A. A. M. Ashik, E. Hossain, M. S. Rahman, S. Islam, S. I. Khan, and M. M. Rahman, “Predictive healthcare analytics: Mental health, vaccination effects, and patient satisfaction,” in Proc. 2025 4th International Conference on Innovative Mechanisms for Industry Applications (ICIMIA), pp. 1934–1947, 2025, doi: 10.1109/ICIMIA67127.2025.11200745.

[15] M. M. Rahman, M. S. Rahman, S. Islam, S. I. Khan, A. A. M. Ashik, E. Hossain, and A. Tanvir, “Integrating data analytics into health informatics: Advancing equity, pharmaceutical outcomes, and public health decision-making,” Eurasian Journal of Medicine and Oncology, vol. 9, no. 4, pp. 284–295, 2025. doi: 10.36922/EJMO025300319.

[16] R. S. Mondal, M. Kamruzzaman, S. Saha, and M. N. A. Bhuiyan, “Quantum machine learning approaches for high-dimensional cancer genomics data analysis,” Computer Integrated Manufacturing Systems, vol. 31, no. 1, pp. 13-32, 2025. doi: 10.24297/j.cims.2025.1.21.

[17] S. Saha, M. K. Islam, M. A. Rahaman, R. S. Mondal, and M. Kamruzzaman, “Machine learning driven analytics for national security operations: A wavelet–stochastic signal detection framework,” Journal of Computational Analysis and Applications, vol. 33, no. 8, Art. no. 210, 2024, doi: 10.48047/jocaaa.2024.33.08.210.

[18] J. Hassan, C. R. Barikdar, S. N. Hasan, J. Kaur, P. Chakraborty, M. A. Miah, and M. A. Goffer, “Blockchain integration in management information systems: A decentralized approach to strengthening cybersecurity and data integrity,” in Proc. 2025 5th International Conference on Electrical, Computer and Energy Technologies (ICECET), Paris, France, pp. 1–7, 2025, doi: 10.1109/ICECET63943.2025.11472020.

[19] S. Bauskar, R. K. Sahoo, S. S. Boda, H. Singhai, M. M. Bakhsh, and M. Adnan, “Privacy-aware big data governance framework using blockchain,” in Proc. 2025 IEEE International Conference on Emerging Trends in Computing and Communication (ETCOM), pp. 1–9, 2025, doi: 10.1109/ETCOM66606.2025.11436976.

[20] U. K. R. Gangula, M. A. Miah, K. Mula, M. Dhakan, Q. T. Sadat, and S. Nayak, “A lightweight and secure semantic communication architecture for edge–IoT–6G systems,” IEEE Communications Standards Magazine, 2026, doi: 10.1109/MCOMSTD.2026.3677038.

[21] M. R. H. Mahin, P. Chakraborty, N. Das, H. Kaur, H. U. Himel, J. Kaur, and A. G. Mohapatra, “Secured and standardized intelligent zero-touch 6G framework for edge-AI applications,” IEEE Communications Standards Magazine, 2026, doi: 10.1109/MCOMSTD.2026.3660159.

[22] M. K. Ahmed, E. Rozario, S. C. Mohonta, J. Ferdousmou, A. S. M. Saimon, M. Moniruzzaman, M. M. T. G. Manik, and R. Hasan, “Leveraging big data analytics for personalized cancer treatment: An overview of current approaches and future directions,” Journal of Engineering, vol. 2025, Art. no. 9928467, 2025, doi: 10.1155/je/9928467.

[23] M. M. T. G. Manik, S. C. Mohonta, F. Karim, M. A. Miah, M. S. Islam, M. A. R. Chy, M. Adnan, and A. S. M. Saimon, “AI-driven precision medicine leveraging machine learning and big data analytics for genomics-based drug discovery,” Journal of Posthumanism, vol. 5, no. 1, pp. 1560–1580, 2025, doi: 10.63332/joph.v5i1.1993.

[24] I. Zerine, M. M. Islam, M. A. U. Khan, M. A. R. Chy, A. S. M. Saimon, M. M. T. G. Manik, and C. Wata, “Explainable churn prediction in telecom with tabular ML five model benchmark and SHAP analysis,” Discover Artificial Intelligence, vol. 6, Art. no. 263, 2026, doi: 10.1007/s44163-026-00983-0.

[25] K. Khan, R. Islam, R. Ali, and H. F. Bernard, “Artificial Intelligence and Data Analytics in Fire Science: Detection, Modeling, and Suppression,” International Journal of Applied and Natural Sciences, vol. 3, no. 2, pp. 132–141, 2025. doi: 10.61424/ijans.v3i2.439.

[26] U. Haldar, S. Sultana, K. B. Siddiqa, E. Rozario, M. A. Miah, H. Rahman, and M. A. R. Chy, “Blockchain-driven access control and compliance auditing framework for federated cloud service providers: Architecture, prototype and evaluation,” in Lecture Notes in Networks and Systems, vol. 1773, G. N. Nguyen, A. Swaroop, and P. Shukla, Eds. Springer, 2026, doi: 10.1007/978-3-032-14197-2_41.

[27] S. H. Rabbani, M. M. Rahman, M. Ahmad, M. Zunayed, and M. R. K. Khan, “Blockchain-based food traceability system to ensure food security in Bangladesh,” in Proc. 2025 International Conference on Circuit, Systems and Communication (ICCSC), pp. 1–6, 2025, doi: 10.1109/ICCSC66714.2025.11135217.

[28] M. R. Habib, M. A. Yusuf, W. M. H. N. Warnasuriya, K. Sunny, M. M. Rahaman, and M. R. K. Khan, “A comprehensive review on the advancement of home automation system,” in Proc. 2024 Second International Conference on Intelligent Cyber Physical Systems and Internet of Things (ICoICI), pp. 638–642, 2024, doi: 10.1109/ICoICI62503.2024.10696135.

[29] M. A. Yusuf, M. R. K. Khan, P. P. Saha, and M. M. Rahaman, “Data fusion of semantic and depth information in the context of object detection,” in Proc. 2024 Second International Conference on Intelligent Cyber Physical Systems and Internet of Things (ICoICI), pp. 1124–1129, 2024, doi: 10.1109/ICoICI62503.2024.10696627.

[30] M. A. Yusuf, N. M. Chowdhury, P. D. Rone, P. P. Saha, M. I. Hossan, D. Sarkar, R. Paul, M. R. Hossain, and M. Chakraborty, “Advancing public safety with real-time life jacket detection and demographic profiling using YOLOv8 and age classification,” EAI Endorsed Transactions on AI and Robotics, vol. 4, pp. 1–12, 2025, doi: 10.4108/airo.9785.

[31] M. M. Rahman, F. F. Sifat, R. Islam, S. Molla, and M. R. K. Khan, “Hybrid recommendation systems using adaptive clustering to address cold start problems,” in Proc. 2024 International Conference on Electrical, Computer and Energy Technologies (ICECET), pp. 1–6, 2024, doi: 10.1109/ICECET61485.2024.10698666.

[32] P. P. Saha, M. M. Rahaman, M. T. Islam, and N. I. Chowdhury, “Advancing lung cancer diagnosis: A hybrid feature fusion approach with attention mechanisms and vision transformer,” in Proc. 2025 2nd International Conference on Intelligent Systems for Cybersecurity (ISCS), pp. 1–7, 2025, doi: 10.1109/ISCS69371.2025.11386016.

[33] P. P. Saha, P. D. Rone, D. Sarkar, M. A. Yusuf, M. I. Hossan, and M. S. J. Mazumder, “Advancing carbon emission prediction through machine learning: The impact of fossil, nuclear, and renewable energies,” in Proc. 2025 International Conference on Emerging Smart Computing and Informatics (ESCI), pp. 1–7, 2025, doi: 10.1109/ESCI63694.2025.10988213.

[34] S. Huang, N. Papernot, I. Goodfellow, Y. Duan, and P. Abbeel, “Adversarial attacks on neural network policies,” arXiv, 2017.

[35] S. M. M. Uddin, M. A. R. Chy, T. R. Sikder, M. I. Faruk, M. Adnan, and M. J. Hossain, “Bio-cognitive AI systems for predictive healthcare decision support,” in Proc. 2025 1st International Conference on Advancement in Futuristic Technologies (ICAFT), Belagavi, India, pp. 1–9, 2025, doi: 10.1109/ICAFT66710.2025.11453175.

[36] S. Bhuiyan and J. S. Park, “Cybersecurity threats and mitigation strategies in AI applications,” Journal of The Colloquium for Information Systems Security Education, vol. 12, no. 1, Art. no. 7, 2025, doi: 10.53735/cisse.v12i1.199.

[37] M. L. Rahman, M. I. Alam, R. Anzum, S. Acharjee, M. S. Alam, and S. Shamarukh, “AI-driven predictive analytics for supply chain resilience, financial risk management, and digital marketing strategy: A unified business intelligence framework,” Journal of Business and Management Studies, vol. 8, no. 7, pp. 41–55, 2026. doi: 10.32996/jbms.2026.8.7.3.

[38] M. I. Alam, R. A. M. Rashed, P. Chakraborty, S. C. Mohonta, H. Imam, and M. M. Rahman Bhuiyan, “Hybrid big data-LLM framework for intelligent scientific literature mining,” in Proc. 2026 IEEE International Conference for Convergence in Computing Technology (I3CTCON), pp. 1–9, 2026, doi: 10.1109/I3CTCON68242.2026.11507315.

[39] M. J. Hossain, M. M. Bakhsh, M. A. Sami, M. I. Alam, M. M. H. Melon, and M. M. T. G. Manik, “Self-adaptive artificial intelligence systems for large-scale data-driven decision making,” in Proc. 2026 IEEE International Conference for Convergence in Computing Technology (I3CTCON), pp. 1–8, 2026, doi: 10.1109/I3CTCON68242.2026.11507252.

[40] R. Sommer and V. Paxson, “Outside the closed world: On using machine learning for network intrusion detection,” in Proc. IEEE Symposium on Security and Privacy, 2010.

[41] M. T. Ribeiro, S. Singh, and C. Guestrin, “Why should I trust you? Explaining the predictions of any classifier,” in Proc. KDD, 2016.

[42] P. Chakraborty, M. A. Miah, M. A. Siam, H. Imam, K. B. Siddiqa, and H. Rahman, “Trustworthy data lakehouse design using federated learning and blockchain,” in Proc. 2025 1st International Conference on Advancement in Futuristic Technologies (ICAFT), pp. 1–8, 2025, doi: 10.1109/ICAFT66710.2025.11453041.

[43] M. Raihan, M. Adnan, M. J. Hossain, K. B. Siddiqa, F. Karim, and S. C. Mohonta, “Adversarial robustness mechanism for safeguarding biometric verification across mobile financial applications,” in Proc. 2025 International Conference on Electrical Engineering and Informatics (ICEEI), pp. 1–7, 2026, doi: 10.1109/ICEEI68459.2025.11330502.

[44] N. Das, S. Sultana, M. S. Sikder, H. U. Himel, U. S. Saha, and R. A. M. Rashed, “AI-enhanced privacy preservation using homomorphic federated models,” in Proc. 2025 1st International Conference on Advancement in Futuristic Technologies (ICAFT), pp. 1–8, 2025, doi: 10.1109/ICAFT66710.2025.11453096.

[45] A. L. Buczak and E. Guven, “A survey of data mining and machine learning methods for cyber security intrusion detection,” IEEE Communications Surveys & Tutorials, vol. 18, no. 2, pp. 1153–1176, 2016.

[46] M. A. Sami, M. A. K. P. Hemal, M. I. Alam, and M. L. Rahman, “Data Governance and Analytics Infrastructure for Scalable Decision-Making in Development and Agritech Programs,” European Journal of Applied Science, Engineering and Technology, vol. 2, no. 2, pp. 388-403, 2024. doi: 10.59324/ejaset.2024.2(2).28.

[47] M. I. Alam, T. R. Sikder, M. A. Sami, M. L. Rahman, M. A. K. P. Hemal, A. A. Linkon, M. M. R. Bhuiyan, M. M. Aziz, M. S. Islam, and M. M. Rahman, “A robust and explainable approach to crop recommendation using a balanced multi-crop agronomic dataset,” Journal of Environmental and Agricultural Studies, vol. 7, no. 3, pp. 1-15, 2026. doi: 10.32996/jeas.2026.7.3.1.

[48] M. M. Hasan, M. I. Alam, M. A. H. Chowdhury, and M. M. Anwar, “AI-Driven Big Data Analytics for Precision Medicine and Healthcare Intelligence: A Unified Framework for Cancer, Chronic Disease, and Clinical Decision Optimization,” Frontiers in Computer Science and Artificial Intelligence, vol. 5, no. 2, pp. 41-62, 2026. doi: 10.32996/jcsts.2026.5.1.5.

[49] T. R. Sikder, M. A. Siam, M. M. H. Melon, S. M. M. Uddin, S. C. Mohonta, and F. Karim, “A Multimodal Data Analytics Framework for Early Cancer Detection Using Genomic, Radiomic, and Clinical Big Data Fusion,” Journal of Computer Science and Technology Studies, vol. 5, no. 3, pp. 183-188, 2023. doi: 10.32996/jcsts.2023.5.3.13.

[50] M. I. Alam, M. A. Sami, M. A. K. P. Hemal, and M. L. Rahman, “Predictive Analytics and Decision Intelligence for Climate-Resilient Agritech Systems,” Academica Global: Journal of Computer Science and Technology Studies, vol. 2, no. 1, pp. 44-56, 2023. doi: 10.32996/agjcsts.2023.2.1.4.

[51] M. I. Alam, M. A. K. P. Hemal, M. A. Sami, and M. L. Rahman, “Robust and Interpretable Crop Recommendation: A Case Study on a Balanced Multi-crop Agronomic Dataset,” European Journal of Ecology, Biology and Agriculture, vol. 1, no. 5, pp. 168-184, 2024. doi: 10.59324/ejeba.2024.1(5).14.

[52] M. I. Alam, M. A. Sami, A. Al Masud, H. Ahmed, and F. Hossain, “AI-Driven Big Data Analytics for Personalized Cancer Treatment: Integrating Multi-Omics, Medical Imaging, and Predictive Intelligence,” Journal of Computer Science and Technology Studies, vol. 7, no. 11, pp. 428-441, 2025. doi: 10.32996/jcsts.2025.7.11.40.

[53] N. Das et al., “AI-driven threat detection and response framework,” International Cybersecurity Law Review, 2026.

[54] M. A. K. P. Hemal, N. Sayeed, M. A. Sami, M. I. Alam, T. R. Sikder, S. A. Dipa, and M. L. Rahman, “Leveraging data analytics to strengthen public health and global economic sustainability,” European Journal of Medical and Health Research, vol. 3, no. 4, pp. 253–263, 2025, doi: 10.59324/ejmhr.2025.3(4).37.

[55] R. S. Mondal, R. A. Ahmed, M. A. K. P. Hemal, T. R. Sikder, and B. J. A. Juie, “A multi-omics transformer foundation model for AI-driven early cancer detection using cfDNA and cfRNA: Implications for precision oncology and early intervention in U.S. healthcare systems,” The American Journal of Medical Sciences and Pharmaceutical Research, vol. 8, no. 2, pp. 113–127, 2026, doi: 10.37547/tajmspr/Volume08Isssssue02-17.

[56] R. S. Mondal, M. N. A. Bhuiyan, M. Kamruzzaman, S. Saha, and M. S. Siddiki, “A comparative analysis of outline of tools for data mining and big data mining,” Journal of Business and Management Studies, vol. 7, no. 4, pp. 232–242, 2025. doi: 10.32996/jbms.2025.7.4.14.

[57] R. S. Mondal, T. N. Purba, N. N. Purba, M. M. Rahman, and T. R. Sikder, “AI-driven glycemic instability risk modeling for proactive intervention and chronic disease management in U.S. healthcare systems,” Journal of Medical and Health Studies, vol. 7, no. 1, pp. 29–43, 2026, doi: 10.32996/jmhs.2023.4.6.21.

[58] S. Nusrat, F. Hossain, and T. R. Sikder, “Integrating Wearable Health Data and Environmental Management Analytics for AI-Driven Cardiovascular Disease Prevention,” The Eastasouth Journal of Information System and Computer Science, vol. 2, no. 02, pp. 209–223, 2024. doi: 10.58812/esiscs.v2i02.868.

[59] S. Nusrat, H. Murshed, and S. Afrin, “Antibiotic resistance at the human–animal–environment crossroads: A systematic review of the silent global pandemic,” Microbial Bioactives, vol. 8, no. 1, pp. 1–7, 2025. doi: 10.25163/microbbioacts.8110426.

[60] M. M. Rahman, S. Sarker, M. M. Hasan Shaikat, S. Das, and M. R. K. Khan, “Machine learning for breast cancer classification: A comparative study of grid search-optimized SVM, random forest, and XGBoost,” in Proc. 2025 International Conference on Quantum Photonics, Artificial Intelligence, and Networking (QPAIN), pp. 1–6, 2025, doi: 10.1109/QPAIN66474.2025.11172245.

[61] K. B. Siddiqa, H. Rahman, C. R. Barikdar, S. M. Orthi, M. A. Miah, and R. Rahman, “AI-driven project management systems: Enhancing IT project efficiency through MIS integration,” in Proc. 2024 International Conference on Progressive Innovations in Intelligent Systems and Data Science (ICPIDS), pp. 114–119, 2024, doi: 10.1109/ICPIDS65698.2024.00027.

[62] K. B. Siddiqa, H. Rahman, H. Imam, M. T. B. Ansar, A. Al Zaiem, A. S.-A. Alahi, and M. M. T. G. Manik, “Assessment of survivability and importance analysis for networks managing intricate traffic flows,” IEEE Communications Standards Magazine, 2025. doi: 10.1109/MCOMSTD.2025.3638981.

[63] T. R. Sikder, S. Dash, B. Uddin, and F. Hossain, “AI-Powered Data Analytics and Multi-Omics Integration for Next-Generation Precision Oncology and Anticancer Drug Development,” The Eastasouth Journal of Information System and Computer Science, vol. 1, no. 02, pp. 153–170, 2023. doi: 10.58812/esiscs.v1i02.838.

[64] T. R. Sikder, N. Sayeed, M. J. Hossain, M. I. Faruk, M. I. Alam, S. M. M. Uddin, and M. Adnan, “AI-Driven Environmental Precision Oncology: Integrating Big Data, Multi-Omics, Medical Imaging, and Exposomic Intelligence for Personalized Cancer Care,” International Journal of Computational and Experimental Science and Engineering, vol. 11, no. 4, 2025. doi: 10.22399/ijcesen.4533.

[65] N. Vanu, M. R. Hasan, T. R. Sikder, and Z. S. Tamanna, “AI-Driven Big Data Analytics for Precision Medicine: A Unified Framework Integrating Molecular Data Intelligence, Wearable Health Systems, and Predictive Modeling,” Journal of Computer Science and Technology Studies, vol. 3, no. 2, pp. 124-141, 2021. doi: 10.32996/jcsts.2021.3.2.11.

[66] P. P. Saha, R. Paul, M. R. K. Khan, N. A. S. Siddique, and B. D. Sarker, “AI-driven modernization of medicare and medicaid enterprise systems: interoperability, claims analytics, and fraud detection frameworks,” Journal of Intelligent Decision Making and Information Science, vol. 3, no. 5s, pp. 827–866, 2026, doi: 10.59543/jidmis.v3.1223.