Semantic AI-Orchestrated Cross-Domain Automation Framework for Sustainable Smart Factories
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Abstract
Manufacturing sectors pursuing Industry 5.0 objectives increasingly require automation architectures capable of reasoning across heterogeneous cyber-physical domains while advancing sustainability targets. This paper synthesizes evidence from eighteen references spanning semantic web technologies, cyber-physical systems, digital twins, blockchain-enabled traceability, and multi-agent reinforcement learning to propose a Semantic AI-Orchestrated Cross-Domain Automation Framework for sustainable smart factories. The framework integrates a five-layer architecture, comprising physical sensing, cyber-physical integration, semantic reasoning, cross-domain orchestration, and sustainability decision layers, into a unified reasoning pipeline in which ontology-driven knowledge graphs mediate interoperability among heterogeneous equipment, enterprise systems, and human operators. Comparative synthesis indicates that semantic-based autonomous computing architectures reduce unplanned downtime by as much as 37 percent, while multi-agent reinforcement learning scheduling raises resource utilization to 88 percent relative to 58 percent under conventional rule-based scheduling. Interoperability standards such as OPC-UA demonstrate adoption rates near 78 percent among reviewed implementations, and hybrid semantic-blockchain ledgers achieve transaction throughput exceeding 2,100 transactions per second at latencies below 40 seconds, outperforming public proof-of-work ledgers by more than two orders of magnitude. Digital twin adoption trajectories synthesized from the references rose from approximately 8 percent in 2016 to 66 percent by 2024, correlating with a 24 percent reduction in energy consumption and a 31 percent reduction in material waste across reviewed sustainable manufacturing cases. The findings imply that semantic orchestration, combined with decentralized ledgers and human-centric digital twins, offers a scalable pathway toward resilient, low-carbon, and economically viable smart factory operations, while highlighting persistent challenges in ontology standardization, explainability, and cross-organizational governance.
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References
[1] I. Bucci, V. Fani, and R. Bandinelli, “Towards Human-Centric Manufacturing: Exploring the Role of Human Digital Twins in Industry 5.0,” Sustainability, vol. 17, no. 1, p. 129, 2025, doi: 10.3390/su17010129.
[2] J. Leng et al., “Towards resilience in Industry 5.0: A decentralized autonomous manufacturing paradigm,” J. Manuf. Syst., vol. 71, pp. 95–114, 2023, doi: 10.1016/j.jmsy.2023.08.023.
[3] L. Monostori et al., “Cyber-physical systems in manufacturing,” CIRP Ann. - Manuf. Technol., vol. 65, no. 2, pp. 621–641, 2016, doi: 10.1016/j.cirp.2016.06.005.
[4] A. Napoleone, M. Macchi, and A. Pozzetti, “A review on the characteristics of cyber-physical systems for the future smart factories,” J. Manuf. Syst., vol. 54, pp. 305–335, 2020, doi: 10.1016/j.jmsy.2020.01.007.
[5] S. J. Oks et al., “Cyber-Physical Systems in the Context of Industry 4.0: A Review, Categorization and Outlook,” Inf. Syst. Front., vol. 26, no. 5, pp. 1731–1772, 2024, doi: 10.1007/s10796-022-10252-x.
[6] F. Z. Amara, M. Djezzar, M. Hemam, and S. M. Tiwari, “A real-time semantic based approach for modeling and reasoning in Industry 4.0,” Int. J. Inf. Technol., vol. 16, no. 1, pp. 507–515, 2024, doi: 10.1007/s41870-023-01640-w.
[7] V. R. Sampath Kumar et al., “Ontologies for Industry 4.0,” Knowl. Eng. Rev., vol. 34, p. e17, 2019, doi: 10.1017/S0269888919000109.
[8] K.-J. Kwak and J.-M. Park, “A Study on Semantic-Based Autonomous Computing Technology for Highly Reliable Smart Factory in Industry 4.0,” Appl. Sci., vol. 11, no. 21, p. 10121, 2021, doi: 10.3390/app112110121.
[9] M. R. Naqvi, L. Elmhadhbi, A. Sarkar, B. Archimede, and M. H. Karray, “Survey on ontology-based explainable AI in manufacturing,” J. Intell. Manuf., vol. 35, no. 8, pp. 3605–3627, 2024, doi: 10.1007/s10845-023-02304-z.
[10] F. Bahrpeyma and D. Reichelt, “A review of the applications of multi-agent reinforcement learning in smart factories,” Front. Robot. AI, vol. 9, p. 1027340, 2022, doi: 10.3389/frobt.2022.1027340.
[11] S. Chorghe, R. Kumar, M. S. Kulkarni, V. Pandhare, and B. K. Lad, “Smart scheduling for next generation manufacturing systems: A systematic literature review,” J. Intell. Manuf., vol. 36, no. 7, pp. 4447–4476, 2025, doi: 10.1007/s10845-024-02484-2.
[12] M. Alazab and S. Alhyari, “Industry 4.0 Innovation: A Systematic Literature Review on the Role of Blockchain Technology in Creating Smart and Sustainable Manufacturing Facilities,” Information, vol. 15, no. 2, p. 78, 2024, doi: 10.3390/info15020078.
[13] J. Leng et al., “Blockchain-empowered sustainable manufacturing and product lifecycle management in Industry 4.0: A survey,” Renew. Sustain. Energy Rev., vol. 132, p. 110112, 2020, doi: 10.1016/j.rser.2020.110112.
[14] S. Hu et al., “Digital Twins Enabling Intelligent Manufacturing: From Methodology to Application,” Intell. Sustain. Manuf., vol. 1, no. 1, p. 10007, 2024, doi: 10.35534/ism.2024.10007.
[15] M. Timperi, K. Kokkonen, and L. Hannola, “Digital twins for environmentally sustainable and circular manufacturing sector: Visions from industry professionals,” Prod. Manuf. Res., vol. 12, no. 1, p. 2428249, 2024, doi: 10.1080/21693277.2024.2428249.
[16] S. M. M. Sajadieh and S. Do Noh, “A Review of Digital Twin Integration in Circular Manufacturing for Sustainable Industry Transition,” Sustainability, vol. 17, no. 16, p. 7316, 2025, doi: 10.3390/su17167316.
[17] T. Burns, J. Cosgrove, and F. Doyle, “A review of interoperability standards for Industry 4.0,” Procedia Manuf., vol. 38, pp. 646–653, 2019, doi: 10.1016/j.promfg.2020.01.083.
[18] V. V. Kumar and K. Shahin, “Artificial Intelligence and Machine Learning for Sustainable Manufacturing: Current Trends and Future Prospects,” Intell. Sustain. Manuf., vol. 2, no. 1, p. 10002, 2025, doi: 10.70322/ism.2025.10002.